OK, we lost two races we were watching closely last night: the attempts to up-end Spencer Bachus and Jo Bonner in Alabama. Both were races targeted by Campaign for Primary Accountability, the SuperPAC that helped end the rein of Jean Schmidt.
Spencer Bachus has his own scandal giving rise of a House Ethics Committee investigation (which undoubtedly will result in prolonged delays followed by a whitewash) and Jo Bonner chairs that Committee-- ground zero for the enablement of corruption in Congress.
National Review has a nice synopsis of both here.
Bottom line: Establishment-oriented incumbents are in trouble.